Apoquel is a newly released prescription medication for allergic dermatitis.Will Apoquel (oclacitinib) revolutionize the treatment of allergic dermatitis? I would like to know , however the shortage of the product will continue to make it’s effectiveness a mystery until the supply is increased.
Allergic dermatitis is a response by the immune system to release allergy-related proteins. The chemicals such as histamines, cytokines, prostaglandins and leukotrienes results in inflammation, pain and “misery” . The cascade of production of these innate chemicals will accumulate and synergistically make the reactions last longer. Once the patient reacts they may scratch, dig, chew or mutilate themselves until the pain overrides the symptoms of the allergic chemicals. If pain is produced, often the animal will leave the area alone. Pain and secondary infection occur.
Typical treatment of allergies includes: antihistamines, shampoo therapy, allergy immunotherapy , steroids and immunosuppressive therapy. Not one works 100%. Often there are side effects. Oclacitinib is not a corticosteroid or antihistamine. While this new drug might not be the first line of treatment, it may be next on the list your DVM will use IF the drug becomes reliably available. Oclacitinib is a plausible alternative to long-term corticosteroids or if corticosteroids are contraindicated such as in cases of diabetes or pancreatitis.
The manufacturer Zoetis has tried to pin down a reliable release date. The dates keep changing but we are hopeful. We will keep you posted.